Award of the Maresch-Klingelhöffer Prize

Prof. Jindrich Cinatl, Dr. Constanze Schneider, Dr. Jürgen Vogt

As part of the ceremony to mark the 25th anniversary of the Frankfurt Foundation for Children with Cancer in November 2019, Dr. Constanze Schneider was awarded the Maresch-Klingelhöffer Prize.

The prize has been awarded since 2008. It has its origin in an endowment by the couple Dr. Otto Maresch and Doris Maresch-Klingehöffer. The prize, endowed with 10,000 euros, honours the best scientific work of young scientists in paediatric cancer research and related fields.

Dr. Constanze Schneider received the award for her scientific paper: “SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukaemia”, which was published in the journal “Nature Medicine”.

Until now, it has not been possible to predict which patients with acute myeloid leukaemia (AML) would respond to the standard chemotherapeutic agent Cytarabine. With SAMHD1- a new biomarker was discovered that can be used to identify patients who respond to chemotherapy with a high degree of accuracy.