Research helps – Not only now
Childhood cancer hits everyone involved like a “bolt from the blue”. From one moment to the next, the view of the world changes, the focus of life shifts. The affected child, the parents, even the entire environment usually fall into a “deep hole”. Despair and struggling with fa…
Visualizing Molecular Patterns of Membrane TNF Receptors using single-molecule microscopy
The question of whether a sick cell dies, divides, or travels through the body is regulated by signal molecules that bind and activate receptors on the cell membrane. Among the most important molecular cues in the immune system is Tumor Necrosis Factor α (TNFα) that binds to TNF…
25 years plus 1 – A review
In September 1994, the Frankfurt Foundation for Children with Cancer was established with the aim of developing new therapy concepts and treatment options for children with cancer. In November 2019, under the patronage of Hesse’s Prime Minister Volker Bouffier, it celebrated its…
Blood cancer: When drugs work
New marker found for the treatment of leukaemia patients
Patients suffering from acute myeloid leukaemia (AML) – a certain form of blood cancer – are treated with the help of chemotherapy. Often, the active substances Decitabine and Azacitidine – so-called DNA methyltransferase…
Financial resources for research
Dr. Sjoerd van Wijk, group leader at the Institute of Experimental Cancer Research in Pediatrics, received a research grant from the German Research Foundation (DFG) to further expand his own research group working on the regulation of ubiquitination in cell fate control. Previo…
Funding for Mildred Scheel Young Investigators Centre
The Mildred Scheel Young Investigators Centre in Frankfurt, whose spokesperson is Prof. Simone Fulda, is receiving funding of 10 million euros from German Cancer Aid. This makes the Department of Medicine at Goethe University and the University Hospital Frankfurt one of only fiv…
Breakthrough in leukaemia therapy
Movie/image: Influence of the cellular enzyme SAMHD1 on the antitumour effect of cytarabine (Ara-C) in acute myeloid leukaemia (AML) – cell line THP-1. Copyright Cinatl et al.
Until now, it has been impossible to predict which patients suffering from acute myeloid leukaemia (AM…
Press release
Prof. Dr. Jindrich Cinatl
First steps on the way to a new cancer drug
Researchers from Frankfurt and Kent successful in finding ways to overcome resistance
FRANKFURT. Researchers from Goethe University and the University of Kent (UK) have found the first step towards a new gener…
